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Scientists Use Stem Cells, Skin Cells to Create Brain Cells Lost to Alzheimer's
Sunday, March 06, 2011
- Business Week (HealthDay News) |
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In what experts are calling a significant step forward in Alzheimer's research, scientists have for the first time turned human embryonic stem cells and a form of human skin cell into a type of brain cell that's lost to Alzheimer's disease.
The disease-induced destruction of these cells, which are called "basal forebrain cholinergic" (BFC) neurons, is key to the progression of Alzheimer's. Their death, say researchers, leads to memory-retrieval problems, one of the most disabling aspects of the illness. Similarly, BFC loss also impairs spatial learning.
But the new study suggests that scientists could someday create a virtually unlimited supply of these neurons in a laboratory setting.
Read more at Business Week.
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Related Articles:
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- FDA Approves Neuralstem’s Drug Trial For Major Depression - ($) (Saturday, December 18, 2010)
Neuralstem, Inc. of Rockville, Md., (CUR) said on December 16 that the U.S. FDA has approved its Investigational New Drug (IND) application to initiate a Phase 1a safety trial to test NSI-189, its first small molecule compound, in major depression.
- Genetic Abnormalities Found In Some Stem Cell Lines (Friday, January 07, 2011)
People have pinned a lot of hopes on pluripotent stem cells -- which, because of their amazing capacity to morph into other types of cells, have been touted as a potential source for replacement tissues that might someday help reverse spinal cord injuries, Alzheimer's disease, and even the damage caused by heart attacks.
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